excitotoxic stress

Excitotoxicity is the pathological process by which nerve cells are damaged and killed by glutamate and similar substances.

Intermittent fasting has shown reduced serum glucose and insulin levels and increased resistance of neurons in the brain to excitotoxic stress.

There is some evidence that intermittent fasting may have beneficial effects on the health and longevity of animals—including humans—that are similar to the effects of caloric restriction (CR).

Calorie restriction, or caloric restriction (CR), is a dietary regimen that restricts calorie intake, where the baseline for the restriction varies, usually being the previous, unrestricted, intake of the subjects. CR, when not associated with malnutrition, has been shown to improve age-related health and to slow the aging process in a wide range of animals and some fungi.

“increased resistance of neurons in the brain to excitotoxic stress” - nice